Month: October 2023

DNA damage is the term for a change in the DNA’s structure, and it can cause mutations and cellular malfunction among other harmful outcomes. Only a few of the various sources of DNA damage include ageing, radiation, and environmental toxins. Kidney cancer, renal disease, and inflammation are just a few of the negative consequences of DNA damage that can occur in the kidney. A few conditions and dysfunctions that can be caused by mutations in …

Introduction The narrowing and stiffening of the kidney’s tiny arteries is the main cause of the prevalent ailment nephrosclerosis. It is characterised by a higher mortality and cardiovascular event risk. According to recent research, the existence of a cyclooxygenase (COX) enzyme system malfunction is one of the primary causes of the progression of nephrosclerosis. As it aids in controlling physiological processes including inflammation, growth, and tissue repair, this enzyme system is crucial for the health …

It was only recently that the name “autosomal dominant tubulointerstitial kidney disease” (ADTKD) was developed to refer to a group of rare inherited kidney diseases. These conditions are characterised by high levels of creatinine and a chronic renal illness that advances slowly. Symptoms of ADTKD may go undiagnosed until the creatinine level is raised because to the autosomal dominant inheritance of the disease.  Dialysis or a kidney transplant may be necessary between the fourth and …

Malnutrition is a term used to describe any abnormal nutritional status leading to either ectomorphism or obesity. Various reasons constitute malnutrition extending from unhealthy or insufficient diet to organ system damage. Kidney disease and liver disease are the major factors that constitute malnutrition when the intake of nutritious food is not a topic of concern.  Dialysis is a continuous mechanical cleansing unit that artificially purifies blood through an external circuit. This in turn means kidney …

Introduction. Intravenous fluids or iv fluids are the medically modified liquids that are administered in the body through injections in the vein.  It is used as the immediate treatment measure for a lot of medical complications, especially dehydration. Intravenous fluids also possess the formulations of specific medications and not just the ability to raise the fluid volume of the body. Saline as commonly termed as dextrose is the most widely used iv fluid to raise …

What are kidney stones?  The formation of renal stones is called nephrolithiasis. It is quite common in India amongst all the age groups and has a better prognosis. Kidney stones or kidney calculi are the solid structures which are made up of various minerals. They can cause severe complications in the body especially in the urinary tract. Oxalate, pyruvate, calcium etc. are the major substances which form kidney stones. Kidney stones are common complications in …

What are steroids? Steroids are artificially prepared chemical compounds that are used for various medical conditions. They are synthetic hormones that have proved to show quick improvement in the muscle and other body part regeneration. They are made up of cyclohexane and cyclopentane rings. Steroids are short acting but quick in their action. Steroids play a role in the symptomatic relief of the conditions which are not entirely treatable or which take a long time …

Basic relation between bone and kidney health. Bone health is intertwined with renal health as vitamin D is processed in the kidneys. Activation of calcitriol occurs in the proximal convoluted tubules of the nephrons. Deterioration of kidney health status adversely affects the bones. Bones when undergoing deterioration they tend to become hypodense. This in turn results in a lower mass of the bone and the destruction of its internal trabecular structure. This condition is grossly …