Pediatric kidney disease

Different conditions of Pediatric kidney disease and its types Pediatric kidney disease is a deteriorating condition that affects the kidneys in children. There are some common types of pediatric kidney disease which includes congenital anomalies of the kidneys and urinary tract, nephrotic syndrome, glomerulonephritis, pyelonephritis, and varying sized kidney stones along with other associated renal complications. The most common type of pediatric kidney disease is congenital anomalies of kidneys and including urinary tract, and they …

Does the size of kidney cysts matter?

 Absolutely Yes, the size of kidney cysts can matter in general. The smaller cysts (less than 1 cm) are considered benign and may not cause symptoms or complications in the initial stage. But larger cysts can potentially cause problems. As kidney cysts grow larger in size, they can put pressure on surrounding tissues, causing pain, discomfort, or complications such as infection or bleeding. Additionally, larger cysts have an increased risk of being cancerous and transforming …

Is it common to lose weight in chronic kidney disease?

Weight loss is commonly seen in chronic kidney disease (CKD) patients, especially in advanced stages but the degree of losing weight varies from person to person. Several factors are associated with this condition like appetite loss, nausea, tiredness, dietary restrictions, muscle wasting, metabolic changes, underlying causes and subsequent stress associated with these. Why do patients lose weight in chronic kidney disease? It is quite common to see patients losing their weight in ckd but these …

The Classical Pathway Triggers Pathogenic Complement Activation in Membranous Nephropathy

The immune system, which aids in defending the body against illness and infection, includes the complement system as a crucial component. It is made up of a number of proteins that cooperate to identify and eliminate outside invaders. The classical pathway is one of the pathways of the complement system, and it is responsible for triggering the activation of the complement proteins. In some cases, this pathway can become overactive and lead to pathogenic complement …

Tuberous Sclerosis Complex

The development of many noncancerous (benign) tumours in various bodily regions is a feature of the hereditary condition known as tuberous sclerosis complex. These tumours can develop in the kidneys, heart, skin, brain, and other organs, and in certain instances, they can significantly harm health. Developmental issues are also brought on by tuberous sclerosis complex, which manifests differently in each individual. Tuberous sclerosis complex frequently affects the brain, and some affected individuals develop cortical tubers, …

Pathological consequences of DNA damage in the kidney

DNA damage is the term for a change in the DNA’s structure, and it can cause mutations and cellular malfunction among other harmful outcomes. Only a few of the various sources of DNA damage include ageing, radiation, and environmental toxins. Kidney cancer, renal disease, and inflammation are just a few of the negative consequences of DNA damage that can occur in the kidney. A few conditions and dysfunctions that can be caused by mutations in …

Influence of variability in the cyclooxygenase pathway on cardiovascular outcomes of nephrosclerosis patients

Introduction The narrowing and stiffening of the kidney’s tiny arteries is the main cause of the prevalent ailment nephrosclerosis. It is characterised by a higher mortality and cardiovascular event risk. According to recent research, the existence of a cyclooxygenase (COX) enzyme system malfunction is one of the primary causes of the progression of nephrosclerosis. As it aids in controlling physiological processes including inflammation, growth, and tissue repair, this enzyme system is crucial for the health …

Autosomal Dominant Tubulointerstitial Kidney Disease

It was only recently that the name “autosomal dominant tubulointerstitial kidney disease” (ADTKD) was developed to refer to a group of rare inherited kidney diseases. These conditions are characterised by high levels of creatinine and a chronic renal illness that advances slowly. Symptoms of ADTKD may go undiagnosed until the creatinine level is raised because to the autosomal dominant inheritance of the disease.  Dialysis or a kidney transplant may be necessary between the fourth and …

Malnutrition in dialysis patients.

Malnutrition is a term used to describe any abnormal nutritional status leading to either ectomorphism or obesity. Various reasons constitute malnutrition extending from unhealthy or insufficient diet to organ system damage. Kidney disease and liver disease are the major factors that constitute malnutrition when the intake of nutritious food is not a topic of concern.  Dialysis is a continuous mechanical cleansing unit that artificially purifies blood through an external circuit. This in turn means kidney …

Different types of intravenous fluids.

Introduction. Intravenous fluids or iv fluids are the medically modified liquids that are administered in the body through injections in the vein.  It is used as the immediate treatment measure for a lot of medical complications, especially dehydration. Intravenous fluids also possess the formulations of specific medications and not just the ability to raise the fluid volume of the body. Saline as commonly termed as dextrose is the most widely used iv fluid to raise …