Stage 2 Kidney Disease represents an early phase of chronic kidney disease. During this stage, there is a gradual and moderate decrease in kidney function. This stage represents an important opportunity to treat the patient and slow down the progression of CKD. By understanding Stage 2 Kidney Disease from the basics, you can take proactive steps to safeguard your kidney health.

In this article, you will learn the following: 

  • Symptoms of Stage 2 Kidney Disease 
  • Causes and Risk Factors 
  • Diagnosis and Medical Tests 
  • Treatment Options
  • Coping Strategies and Lifestyle Modifications 
  • Outlook and Prognosis
  • Frequently asked questions

Symptoms of Stage 2 Kidney Disease

Stage 2 Kidney Disease comes with various symptoms and signs. The symptoms at this stage may not be as noticeable but it is still important to recognize them for early treatment. This is because they can be potential indicators of underlying kidney dysfunction. Some common symptoms include:

  1. Fatigue:

One of the common symptoms of any stage renal disease is fatigue. People may constantly lack energy. It can be attributed to the kidneys’ reduced ability to remove waste products and toxins from the body efficiently.

  1. Change in urine output:

Another symptom to watch for is changes in urine output. It may include an increase or decrease in the frequency of urination, changes in urine color or consistency, or the presence of foamy urine. Such changes are evidence for kidney malfunction. 

  1. Increased blood pressure:

Additionally, people with Stage 2 Kidney Disease may also experience elevated blood pressure levels. Your kidneys have an important role in maintenance of blood pressure. However, when the kidney gets damaged the malfunctioning can lead to hypertension. 

You must monitor your blood pressure regularly and seek medical attention for persistent high readings to efficiently manage Stage 2 Kidney Disease.

Although these symptoms mostly indicate Stage 2 Kidney Disease, they can also be associated with other health conditions. Therefore, you must perform a proper medical evaluation and diagnosis to confirm the presence of Stage 2 Kidney Disease.

Causes and Risk Factors 

Several causes and risk factors can increase the chances of developing Stage 2 Kidney Disease in a person. Understanding these causes and risk factors is essential for early treatment and management of the disease.

Underlying causes leading to Stage 2 Kidney Disease 

  1. Diabetes:

Uncontrolled or poorly managed diabetes is one of the leading causes of kidney disease. High blood sugar levels over time can damage the kidneys’ filtering units, impairing their function.

  1. Increased Blood Pressure:

Long-term increase in blood pressure can put a lot of pressure on the blood vessels present in the kidneys and result in damage. It is a common cause of Stage 2 Kidney Disease.

  1. Glomerulonephritis:

Glomerulonephritis is the inflammation of the kidney’s filtering units – glomeruli. This condition can result from infections, autoimmune diseases, or certain medications.

  1. Polycystic Kidney Disease (PKD):

This is a health condition which is passed from one generation to another. It is distinguished by the growth of multiple cysts in the kidneys. Over time, these cysts can impair kidney function and contribute to Stage 2 Kidney Disease.

  1. Autoimmune Diseases:

Autoimmune diseases like lupus nephritis and vasculitis can affect the kidneys and result in  Stage 2 Kidney Disease. This is because in these diseases, your body mistakes kidney tissues as foreign bodies and attacks them. It leads to inflammation and ultimately, impaired kidney function.

Risk factors leading to Stage 2 Kidney Disease 

  1. Family History:

Having a family history of kidney disease, especially conditions like PKD or other hereditary kidney disorders, increases the risk of developing Stage 2 Kidney Disease.

  1. Age:

The risk of kidney disease generally increases with age. Older adults are more susceptible to kidney damage and functional decline.

  1. Obesity:

Being overweight or obese puts additional strain on the kidneys and increases the risk of developing various kidney conditions, including Stage 2 Kidney Disease.

  1. Smoking:

Smoking negatively affects blood circulation and damages blood vessels, including those in the kidneys. It can contribute to kidney damage and disease progression.

  1. Medications:

Regular usage of certain anti-inflammatory drugs and antibiotics can damage the kidney tissues and contribute to Stage 2 Kidney Disease.

Diagnosis and Medical Tests 

Precise diagnosis is essential to identify and confirm Stage 2 Kidney Disease. This typically involves the following diagnostic procedures and tests:

  1. Blood Tests: 

Blood tests play a crucial role in analyzing  kidney function. There are mainly two blood tests that doctors use to diagnose Stage 2 Kidney Disease. It includes serum creatinine and estimated glomerular filtration rate (eGFR). Elevated levels of creatinine in the blood and a lower eGFR indicate impaired kidney function.

  1. Urine Tests:

Urine tests are conducted to analyze the presence of protein, blood, or other abnormalities in the urine. Increased levels of protein (proteinuria) or blood (hematuria) can indicate kidney damage and dysfunction.

  1. Imaging Studies: 

Imaging techniques, such as ultrasound or CT scans, may be used to visualize the structure and size of the kidneys. The tests can help to recognize abnormalities like cysts or tumors that may contribute to Stage 2 Kidney Disease.

  1. Kidney Biopsy: 

In some rare cases, your doctor may recommend you to undergo a kidney biopsy. It helps to get better insights into the underlying cause of kidney damage. This procedure involves obtaining a small sample of kidney tissue for microscopic examination, providing valuable insights into the specific condition affecting the kidneys.

  1. Medical History and Physical Examination: 

A comprehensive medical history review and physical examination help Nephrologists assess overall health, identify potential risk factors, and evaluate symptoms associated with Stage 2 Kidney Disease.

Treatment Options 

The primary goal of treatment is to control underlying conditions and manage symptoms. To manage Stage 2 Kidney Disease, you may have to undergo the following:

  1. Medications:

Blood pressure medications like ACE inhibitors or ARBs are prescribed to control hypertension and protect the kidneys from further damage. Medications to manage underlying diseases like diabetes or autoimmune diseases, may also be prescribed. Medicines like diuretics or erythropoiesis-stimulating agents (ESAs) may also be recommended. As it will help treat symptoms like fluid retention or anemia.

  1. Lifestyle Changes:

Adopting a kidney-friendly diet with reduced sodium, limited phosphorus and potassium, and moderate protein intake is recommended. Monitoring and regulating fluid intake is crucial. Regular exercise helps control blood pressure and improve overall cardiovascular health. Smoking cessation is necessary to prevent further damage to the kidneys.

  1. Regular Monitoring:

Regular follow-up visits with Nephrologists are essential to monitor kidney function, adjust medications, and assess disease progression. Laboratory tests, including blood and urine tests, are performed periodically to evaluate kidney function, assess proteinuria, and detect complications.

  1. Dietary Protein Restriction:

In some cases, Nephrologists may recommend reducing dietary protein intake. Reduced food intake will decrease the burden on the kidneys. However, you must work with a registered dietitian to ensure that protein restriction is balanced with adequate nutrition.

  1. Blood Sugar Control:

For people who have Stage 2 Kidney Disease along with diabetes, strict blood sugar control is essential. It involves managing blood glucose levels through a combination of medication, dietary modifications, and regular monitoring. By effectively controlling diabetes you can reduce the risk of further kidney damage.

Coping Strategies and Lifestyle Modifications 

Living with Stage 2 Kidney Disease is challenging. However, you can manage kidney disease by implementing these coping strategies and lifestyle modifications in your life.  

  1. Education and Understanding: 

Educating yourself about Stage 2 Kidney Disease is important for coping effectively. Learn about the condition, its symptoms, treatment options, and lifestyle modifications. Understanding the disease empowers you to actively participate in your care, make informed decisions, and manage expectations.

  1. Emotional Support: 

Seek support from your close ones or family members. Share your experiences, concerns, and emotions with others who are going through similar situations. They can provide you a sense of community, empathy, and emotional support. It will help you to have a support system that can offer encouragement, understanding, and practical advice.

  1. Healthy Diet and Fluid Management: 

Follow a kidney-friendly diet recommended by your dietitian. It would normally involve reduced sodium, limiting phosphorus and potassium, and moderating protein intake. Additionally, you must stick to fluid restrictions as it helps to prevent fluid overload and strain on the kidneys. 

  1. Medication Adherence: 

Take prescribed medications as directed by your Nephrologist. Sticking to the prescribed treatment plan is essential for managing symptoms, controlling underlying conditions, and slowing down the progression of Stage 2 Kidney Disease. Consistency in the use of medication ensures the effectiveness of treatment and helps retain kidney function.

  1. Stress Management: 

The best way to manage stress as a CKD patient is to develop some basic stress management techniques. Engage in activities that promote relaxation and peace, such as deep breathing exercises, meditation, yoga, or pursuing hobbies you enjoy. Managing stress positively will have an impact on both your physical and emotional health, and it will help you cope better with the challenges of living with Stage 2 Kidney Disease.

Outlook and Prognosis 

There are several factors that can affect the outlook and prognosis of Stage 2 Kidney Disease. Some of those factors include:

  1. Disease Progression Factors: 

The progression of Stage 2 Kidney Disease can be influenced by various factors. It includes the underlying cause of the disease, the effectiveness of treatment and management strategies, sticking to lifestyle modifications and medication regimens, and control of underlying conditions like diabetes or hypertension.

  1. Timely Intervention: 

Early detection and intervention play an essential role in management of Stage 2 Kidney Disease. By implementing appropriate treatment, lifestyle modifications, and regular monitoring, people can slow down the progression of the disease and preserve kidney function.

  1. Individual Response: 

Each person’s response to treatment and lifestyle modifications may vary depending on age and the presence of other medical conditions. It’s essential to work closely with a Nephrologist to develop a personalized treatment plan and monitor kidney function regularly.

  1. Proactive Management: 

Being proactive in managing the disease can help you slow down the progression of Stage 2 Kidney Disease. You can do this by engaging in active self-care, sticking to medication regimens and following a kidney-friendly diet.

  1. Regular Monitoring: 

Regular follow-up visits and monitoring of kidney function are necessary to assess the progression of the disease and make any necessary adjustments to the treatment plan. Nephrologists will closely monitor your creatinine levels, estimated glomerular filtration rate (eGFR), and proteinuria levels to evaluate kidney function.


Stage 2 Kidney Disease is a manageable condition that requires early detection, proactive treatment, and lifestyle adjustments. Recognizing the symptoms and seeking timely medical intervention is crucial for slowing down the progression of the disease. 

With appropriate medications, dietary changes, and adherence to treatment plans, individuals can effectively manage Stage 2 Kidney Disease and improve their overall outlook. For better guidance, contact the best Nephrologist in India.

Frequently Asked Questions 

  1. Can you recover from stage 2 kidney disease?

Recovery from Stage 2 Kidney Disease is possible through early detection, proper management, and lifestyle modifications. With timely intervention and adherence to treatment plans, individuals can slow down the progression of the disease and preserve kidney function.

  1. How do you cope with kidney disease?

Coping with kidney disease involves educating oneself about the condition, seeking emotional support from family or support groups, following a kidney-friendly diet, adhering to medication regimens, practicing stress management techniques, and maintaining regular communication with your Nephrologist.

  1. Is Stage 2 kidney disease serious?

While Stage 2 Kidney Disease indicates mild kidney damage, it should be taken seriously as it can progress if left untreated. However, with appropriate medical care and lifestyle modifications, individuals can effectively manage the disease and improve their prognosis.